Searchable abstracts of presentations at key conferences in endocrinology

ea0042p10 | (1) | Androgens2016

Metastases-prone localized prostate cancer: a genomic analysis

Van den Broeck Thomas , Gevaert Thomas , Prekovic Stefan , Boeckx Bram , Smeets Elien , Ong Kaye , Lehrer Jonathan , Haddad Zaid , Erho Nicholas , Helsen Christine , Lambrechts Diether , Buerki Christine , Davicioni Elai , Joniau Steven , Claessens Frank

Clinical features of the primary prostate tumor remain insufficient for clinicians to accurately define patients at highest risk of developing metastases. However, the primary tumor is the source of these metastases, and thus should contain information on its metastatic potential. We hypothesized that the combination of a primary tumor’s copy number alterations (CNAs) and genome-wide transcriptome information would give us more insight in the biology of metastases-prone l...